Advertisement
Scientific/Clinical Article| Volume 31, ISSUE 2, P250-254, April 2018

Download started.

Ok

Risk factors for complex regional pain syndrome in patients with surgically treated traumatic injuries attending hand therapy

      Abstract

      Study Design

      Prospective cohort study.

      Introduction

      Identification of risk factors for CRPS development in patients with surgically treated traumatic injuries attending hand therapy allows to watch at-risk patients more closely for early diagnosis and to take precautionary measures as required.

      Purpose of the Study

      The aim of this study was to evaluate the risk factors for the development of complex regional pain syndrome (CRPS) after surgical treatment of traumatic hand injuries.

      Methods

      In this prospective cohort, 291 patients with traumatic hand injuries were evaluated 3 days after surgery and monitored for 3 months for the development of CRPS. The factors assessed for the development of CRPS were age, sex, manual work, postoperative pain within 3 days measured on a Pain Numerical Rating Scale (0-10), and injury type (crush injury, blunt trauma, and cut laceration injury).

      Results

      CRPS was diagnosed in 68 patients (26.2 %) with a duration of 40.10 ± 17.01 days between the surgery and CRPS diagnosis. The mean postoperative pain score was greater in patients with CRPS than in those without CRPS (P < .001). Patients with pain scores ≥ 5 had a high risk of developing CRPS compared with patients with pain scores <5 (odds ratio: 3.61, confidence interval = 1.94-6.70). Patients with crush injuries were more likely to develop CRPS (odds ratio: 4.74, confidence interval = 2.29-9.80).

      Conclusions

      The patients with a pain score of ≥5 in the first 3 days after surgery and the patients with crush injury were at high risk for CRPS development after surgical treatment of traumatic hand injuries.

      Level of Evidence

      II b.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Journal of Hand Therapy
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Źyluk A.
        • Puchalski P.
        Complex regional pain syndrome of the upper limb: A review.
        Neurol Neurochir Pol. 2014; 48: 200-205
        • De Mos M.
        • de Bruijn A.G.
        • Huygen F.J.
        • Dieleman J.P.
        • Stricker B.H.
        • Sturkenboom M.C.
        The incidence of complex regional pain syndrome: A population-based study.
        Pain. 2007; 129: 12-20
        • Marinus J.
        • Moseley G.L.
        • Birklein F.
        • et al.
        Clinical features and pathophysiology of complex regional pain syndrome.
        Lancet Neurol. 2011; 10: 637-648
        • Da Costa V.V.
        • de Oliveira S.B.
        • Fernandes Mdo C.
        • Saraiva R.Â.
        Incidence of CRPS after CTS release. Is there a correlation with the anesthetic technique?.
        Rev Bras Anestesiol. 2011; 61: 425-433
        • Cheung K.
        • Walley K.C.
        • Rozental T.D.
        Management of complications of Dupuytren contracture.
        Hand Clin. 2015; 31: 345-354
        • Takwale V.J.
        • Stanley J.K.
        • Shahane S.A.
        Post-traumatic instability of the trapeziometacarpal joint of the thumb. Diagnosis and the results of reconstruction of the beak ligament.
        J Bone Joint Surg Br. 2004; 86: 541-545
        • Herzberg G.
        • Burnier M.
        • Marc A.
        • Merlini L.
        • Izem Y.
        The role of arthroscopy for treatment of perilunate injuries.
        J Wrist Surg. 2004; 4: 101-109
        • Li Z.
        • Smith B.P.
        • Tuohy C.
        • Smith T.L.
        • Andrew Koman L.
        Complex regional pain syndrome after hand surgery.
        Hand Clin. 2010; 26: 281-289
        • Moseley G.L.
        • Herbert R.D.
        • Parsons T.
        • Lucas S.
        • Van Hilten J.J.
        • Marinus J.
        Intense pain soon after wrist fracture strongly predicts who will develop complex regional pain syndrome: prospective cohort study.
        J Pain. 2014; 15: 16-23
        • Dijkstra P.U.
        • Groothoff J.W.
        • ten Duis H.J.
        • Geertzen J.H.
        Incidence of complex regional pain syndrome type 1 after fractures of the distal radus.
        Eur J Pain. 2003; 7: 457-462
        • Jellad A.
        • Salah S.
        • Ben Salah Frih Z.
        Complex regional pain syndrome type 1: Incidence and risk factors in patients with fracture of the distal radius.
        Arch Phys Med Rehabil. 2014; 95: 487-492
        • Pons T.
        • Shipton E.A.
        • Williman J.
        • Mulder T.R.
        Potential risk factors for the onset of complex regional pain syndrome Type 1: a systematic literature review.
        Anesthesiol Res Pract. 2015; 2015: 956539
        • Roh Y.H.
        • Lee B.K.
        • Noh J.H.
        • et al.
        Factors associated with complex regional pain syndrome type 1 in patients with surgically treated distal radius fracture.
        Arch Orthop Trauma Surg. 2014; 134: 1775-1781
        • Beerthuizen A.
        • Stronks D.L.
        • Van't Spijker A.
        • et al.
        Demographic and medical parameters in the development of complex regional pain syndrome type 1 (CRPS1): prospective study on 596 patients with a fracture.
        Pain. 2012; 153: 1187-1192
        • Demir S.E.
        • Ozaras N.
        • Karamehmetoğlu S.S.
        • Karacan I.
        • Aytekin E.
        Risk factors for complex regional pain syndrome in patients with traumatic extremity surgery.
        Ulus Travma Acil Cerrahi Derg. 2010; 16: 144-148
        • Arcury T.A.
        • Cartwright M.S.
        • Chen H.
        • et al.
        Musculoskeletal and neurological injuries associated with work organization among immigrant Latino women manual workers in North Carolina.
        Am J Ind Med. 2014; 57: 468-475
        • Semer N.B.
        Hand crush injury and compartment syndrome.
        in: Semer N.B. Practical Plastic Surgery for Nonsurgeons. Hanley&Belfus, Inc, Philadelphia2001: 329-338
        • Jensen M.P.
        • Karoly P.
        • Braver S.
        The measurement of clinical pain intensity: a comparison of six methods.
        Pain. 1986; 27: 117-126
        • Harden R.N.
        • Bruehl S.
        • Stanton-Hicks M.
        • Wilson P.R.
        Proposed new diagnostic criteria for complex regional pain syndrome.
        Pain Med. 2007; 8: 326-331
        • Field J.
        • Atkins R.M.
        Algodystrophy is an early complication of Colles’ fracture. What are the implications?.
        J Hand Surg Br. 1997; 22: 178-182
        • Reuben S.S.
        Preventing the development of complex regional pain syndrome after surgery.
        Anesthesiology. 2004; 101: 1215-1224
        • Harden R.N.
        • Bruehl S.
        • Stanos S.
        • et al.
        Prospective examination of pain-related and psychological predictors of CRPS-like phenomena following total knee arthroplasty: a preliminary study.
        Pain. 2003; 106: 393-400
        • Graceley R.H.
        • Lynch S.A.
        • Bennett G.J.
        Painful neuropathy: altered central processing maintained dynamically by peripheral input.
        Pain. 1992; 51: 175-194
        • Birklein F.
        • Schlereth T.
        Complex regional pain syndrome-significant progress in understanding.
        Pain. 2015; 156: 94-103
        • Shibuya N.
        • Humphers J.M.
        • Agarwal M.R.
        • Jupiter D.C.
        Efficacy and safety of high dşe vitamin C on complex regional pain syndrome in extremity trauma and surgery-systematic review and meta-analysis.
        J Foot Ankle Surg. 2013; 52: 62-66
        • Meena S.
        • Sharma P.
        • Gangary S.K.
        • Chowdhury B.
        Role of vitamin C in prevention of complex regional pain syndrome after distal radius fractures: a meta-analysis.
        Eur J Orthop Surg Traumatol. 2015; 25: 637-641
        • Atkins R.M.
        • Duckworth T.
        • Kanis J.A.
        Features of algodystrophy after Colles fracture.
        J Bone Joint Surg Br. 1990; 72: 105-110
        • Hove L.M.
        Nerve entrapment and reflex sympathetic dystrophy after fractures of distal radius.
        Scand J Plast Reconstr Surg Hand Surg. 1995; 29: 53-58
        • Shinya K.
        • Lanzetta M.
        • Conolly W.B.
        Risk and complications in endoscopic carpal tunnel release.
        J Hand Surg Br. 1995; 20: 222-227
        • Crean S.M.
        • Gerber R.A.
        • Le Graverand M.P.
        • Boyd D.M.
        • Cappelleri J.C.
        The efficacy and safety of fasciectomy and fasciotomy for Dupuytren’s contracture in European patients: a structured review of published studies.
        J Hand Surg Eur. 2011; 36: 396-407
        • Veldman P.H.
        • Reynen H.M.
        • Arntz I.E.
        • Goris R.J.
        Signs and symptoms of reflex sympathetic dystrophy: prospective study of 829 patients.
        Lancet. 1993; 342: 1012-1016
        • Harden N.R.
        • Bruehl S.
        • Perez R.S.
        • et al.
        Validation of proposed diagnostic criteria (the ‘Budapest Criteria’) for Complex Regional Pain Syndrome.
        Pain. 2010; 150: 268-274
        • Oaklander A.L.
        • Rissmiller J.G.
        • Gelman L.B.
        • Zheng L.
        • Chang Y.
        • Gott R.
        Evidence of focal small-fiber axonal degeneration in complex regional pain syndrome-I (reflex sympathetic dystrophy).
        Pain. 2006; 120: 235-243
        • Bruehl S.
        Complex regional pain syndrome.
        BMJ. 2015; 351: h2730

      JHT Read for Credit

      Quiz: #545

      Record your answers on the Return Answer Form found on the tear-out coupon at the back of this issue or to complete online and use a credit card, go to JHTReadforCredit.com. There is only one best answer for each question.
      • #1.
        The study design was
        • a.
          RCTs
        • b.
          prospective cohort
        • c.
          retrospective chart reviews
        • d.
          case series
      • #2.
        The PNRS utilized was
        • a.
          0-100
        • b.
          1-100
        • c.
          1-10
        • d.
          0-10
      • #3.
        Initial pain scores were recorded at
        • a.
          the day of surgery
        • b.
          3 days pre op
        • c.
          3 days post op
        • d.
          3 weeks post op
      • #4.
        Tendon repaired patients were treated with
        • a.
          PROM for extensors and AROM for flexors
        • b.
          PROM for flexors and AROM for extensors
        • c.
          PROM for flexors and extensors
        • d.
          AROM for flexors and extensors
      • #5.
        The authors identified patients with crush injuries or pain scores of 5 or greater as at risk to develop CRPS
        • a.
          true
        • b.
          false
      When submitting to the HTCC for re-certification, please batch your JHT RFC certificates in groups of 3 or more to get full credit.