Medication-induced Adverse Effects: Important Concepts for the Hand Therapist
published online 02 March 2010.
Abstract
Narrative Review
Myopathy, fracture, tendon rupture, and neuropathy are severe physical adverse effects associated with commonly prescribed medications. Recognition of and exercise adjustment for these medication-induced effects by the therapist is essential to providing adequate care. The normal structure and function of muscle, tendon, cartilage, or bone may be altered by medications, leading to significant disability. The number of patients presenting to therapists with medication-induced physical complaints is rising with increases in medication utilization. Therapists should be involved in adverse effect risk reduction by 1) identification and reporting of potential adverse medication reactions, 2) adjustment of exercise regimen when the patient is on a medication with potential damaging effects on tendon, muscle, or cartilage, and 3) vigilant screening for medication-induced myopathies, fractures, neuropathies, and tendinopathies. Although many medications induce physical adverse effects, understanding the most serious musculoskeletal effects of commonly prescribed medications is critical for therapists.
Level of Evidence
5.
University of Mississippi School of Pharmacy, Jackson, Mississippi
University of Mississippi School of Medicine, Jackson, Mississippi
Department of Pharmacy Practice and Medicine, University of Mississippi Medical Center, Jackson, Mississippi
University of Mississippi School of Pharmacy, Jackson, Mississippi
University of Mississippi School of Medicine, Jackson, Mississippi
Department of Pharmacy Practice and Medicine, University of Mississippi Medical Center, Jackson, Mississippi
University of Mississippi School of Pharmacy, Jackson, Mississippi
Department of Pharmacy Practice, University of Mississippi, Jackson, Mississippi
Correspondence and reprint requests to Daniel M. Riche, PharmD, BCPS, CDE, Department of Pharmacy Practice and Medicine, University of Mississippi Medical Center, Office Annex Building, WW 120-A, 2500 North State Street, Jackson, MS 39216
ABSTRACT